Product Name: Octyl Salicylate
Synonyms: 2-Ethylhexyl Salicylate, Ethylhexyl Salicylate, Salicylic Acid 2-Ethylhexyl Ester, Escalol 587
CAS Number: 118-60-5
Recommended Use: UV absorber in sunscreens, cosmetics, and personal care products
Manufacturer: Supplier contact information appears on container label
Emergency Contact: Emergency telephone number listed on shipping documents
Revision Date: June 2024
Formula: C15H22O3
Molecular Weight: 250.3 g/mol
GHS Classification: Eye irritation (Category 2A), Skin irritation (Category 2)
GHS Label Elements: Exclamation mark hazard pictogram, Signal Word: Warning
Hazard Statements: Causes skin irritation, causes serious eye irritation, may cause mild respiratory irritation
Precautionary Statements: Avoid skin and eye contact, wear protective gloves, use eye protection, wash hands thoroughly after handling, do not breathe vapors
Potential Health Effects: Eyes – redness, pain; Skin – redness, discomfort; Inhalation – cough, mild irritation; Ingestion – nausea, stomach discomfort
Other Hazards: May cause allergic reactions in sensitive individuals, not classified as carcinogenic or mutagenic by major agencies
Chemical Name: Octyl Salicylate
Common Names: See synonyms
Concentration: 100% (pure substance)
Impurities: Trace amounts of associated esters (typically less than 0.5%)
Additives: None indicated for technical grade product
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present, continue rinsing and seek medical advice
Skin Contact: Wash with plenty of soap and water, remove contaminated clothing, if skin irritation or rash occurs: get medical advice
Inhalation: Move person to fresh air, keep at rest, obtain medical attention if symptoms persist
Ingestion: Rinse mouth, do not induce vomiting, seek medical help if feeling unwell or large amounts swallowed
Advice for Doctor: Treat symptomatically
Suitable Extinguishing Media: Water spray, alcohol-resistant foam, dry chemical, carbon dioxide
Unsuitable Media: Direct water jet (may spread liquid)
Specific Hazards: May form toxic or irritating fumes including carbon monoxide, carbon dioxide
Protective Equipment: Wear self-contained breathing apparatus, full protective suit
Special Procedures: Move containers away from fire if safe, cool containers exposed to flames with water
Personal Precautions: Wear gloves, goggles, protective clothing, ensure adequate ventilation, keep unprotected people away
Environmental Precautions: Prevent entry into sewers, soil, and surface water, do not allow material to contaminate ground water
Cleanup Methods: Absorb spill with inert material like sand or earth, collect and place in suitable closed container, wash spill area with plenty of water after material pickup
Safe Handling: Avoid contact with skin, eyes, and clothing, use in well-ventilated area, keep away from food and drink
Storage Conditions: Store in tightly closed container, keep in cool, dry, well-ventilated space away from heat and ignition sources
Incompatible Materials: Strong oxidizers, acids, alkalis
Hygiene Measures: Wash hands after handling, do not eat, drink, or smoke when using this product
Specific Storage Temperatures: Preferably below 30°C (86°F)
Exposure Limits: No established occupational exposure limits (TLV, PEL), use workplace exposure guidelines for nuisance particulates
Engineering Controls: General exhaust ventilation recommended, local exhaust in confined situations
Personal Protection: Chemical-resistant gloves (nitrile, neoprene), safety goggles, protective clothing, in case of insufficient ventilation use approved respirator
Other Protective Equipment: Eyewash fountain, emergency shower in work area
Environmental Controls: Prevent spills, use secondary containment where feasible
Appearance: Colorless to pale yellow, oily liquid
Odor: Faint, characteristic
pH: Not applicable (insoluble in water)
Boiling Point: 210–215°C (410–419°F) at 1 atm
Melting Point: -30°C (-22°F)
Flash Point: 193–200°C (379–392°F) (closed cup)
Evaporation Rate: Not determined
Flammability: May form combustible mixtures at high temperatures
Vapor Pressure: <0.001 hPa at 20°C
Vapor Density: Not available
Density: 1.007–1.017 g/cm³ (20°C)
Solubility: Practically insoluble in water; soluble in organic solvents (ethanol, oils)
Partition Coefficient (Log Kow): 5.98
Viscosity: 8–12 mPa·s (20°C)
Decomposition Temperature: No data available
Chemical Stability: Stable under recommended handling and storage conditions
Conditions to Avoid: Excessive heat, sparks, open flames
Materials to Avoid: Strong acids, strong bases, oxidizing agents
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, irritating organic vapors
Polymerization: Will not occur under normal process conditions
Acute Toxicity: Oral LD50 (Rat) >5000 mg/kg, Dermal LD50 (Rabbit) >4000 mg/kg
Skin Irritation: May cause mild irritation through repeated or prolonged contact
Eye Irritation: Causes moderate to severe irritation
Respiratory Sensitization: Not expected from brief exposure
Chronic Toxicity: No known long-term toxicity with conventional use
Carcinogenicity: Not classified as hazardous by IARC, NTP, OSHA
Reproductive Toxicity: No evidence in standard animal studies
Other Effects: Large ingestion may produce gastrointestinal symptoms
Human Experience: Sensitization rare but possible
Aquatic Toxicity: LC50 (Fish, 96h) >10 mg/L, EC50 (Daphnia, 48h) >5 mg/L
Persistence: Not readily biodegradable, slow breakdown in environment
Bioaccumulation: Significant potential given high log Kow
Mobility: Low water solubility, tends to adsorb to soils and sediment
Ecotoxicology Notes: Avoid release to waterways, may be toxic to aquatic organisms in high concentrations
Other Environmental Information: Degrades slowly, potential to bioaccumulate
Waste Disposal Methods: Dispose according to local, regional, national, or international regulations, place in properly labeled containers
Contaminated Packaging: Triple rinse, recycle or dispose of safely through authorized waste contractor
Small Spills: Absorb and contain for disposal as chemical waste
Do Not: Dump in drains, natural water systems, or open environment
UN Number: Not regulated for transport
Proper Shipping Name: Not classified as dangerous goods
Transport Hazard Classes: Not assigned
Packing Group: Not assigned
Environmental Hazards: Not a marine pollutant
Special Precautions: Protect containers from physical damage, secure upright during transport
Safety, Health, and Environmental Regulations: Listed in chemical inventories (TSCA, EINECS/ELINCS, DSL)
OSHA Status: Not hazardous as defined by OSHA Hazard Communication Standard
EPA: Not classified as hazardous waste under RCRA
SARA Title III: Not listed on SARA 302, 304, 313
California Prop 65: Not listed
EU Classification: Not classified as hazardous according to Regulation (EC) No. 1272/2008
Labeling Requirements: GHS label elements required, safety phrases for industrial use: S24/25–Avoid contact with skin/eyes
Other National Regulations: Complies with relevant national and regional environmental regulations where sold
