Product Name: Monomethyl Adipate
CAS Number: 627-91-8
Synonyms: Adipic acid monomethyl ester, Hexanedioic acid monomethyl ester
Recommended Use: Chemical intermediate, solvent, laboratory reagent
Restrictions on Use: Industrial or professional use only, keep out of reach of children
Supplier Identification: Manufacturer or distributor address, emergency contact number, business email
Emergency Phone: CHEMTREC, Poison Control Center or company emergency line
GHS Classification: Eye irritation (Category 2A), Skin irritation (Category 2), Specific target organ toxicity – single exposure (Category 3)
Label Elements: Signal word: Warning, Hazard statements: Causes skin irritation, Causes serious eye irritation, May cause respiratory irritation
Pictograms: Exclamation mark
Precautionary Statements: Avoid breathing vapors, wash thoroughly after handling, wear protective gloves and eye protection, use only outdoors or in well-ventilated area
Other Hazards: Vapor may cause mild respiratory tract irritation, contact with skin or eyes can cause discomfort
Chemical Name: Monomethyl Adipate
CAS No.: 627-91-8
Concentration: ≥ 98%
Impurities: Trace amounts of diester and monoacid, no significant hazardous impurities expected
Additives: None declared
Eye Contact: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing until irritation subsides.
Skin Contact: Wash immediately with soap and water. Remove contaminated clothing and wash before reuse. Seek medical attention if irritation persists.
Ingestion: Rinse mouth. Do not induce vomiting unless directed by medical personnel. Get medical help if you feel unwell.
Inhalation: Move to fresh air. Keep comfortable for breathing. Get medical attention if symptoms occur such as coughing or difficulty breathing.
Note to Physician: Symptomatic treatment. No specific antidote known.
Suitable Extinguishing Media: Water spray, foam, dry chemical, carbon dioxide
Unsuitable Media: Straight streams of water may spread fire
Specific Hazards: Vapors may form explosive mixtures with air, thermal decomposition produces irritating fumes (carbon oxides)
Protective Equipment: Full protective gear and self-contained breathing apparatus for firefighters
Advice for Firefighters: Prevent runoff from entering drains or waterways. Cool containers with water spray.
Personal Precautions: Wear gloves, protective clothing, eye and face protection. Ensure adequate ventilation. Evacuate unnecessary personnel.
Environmental Precautions: Prevent product from entering drains, surface waters or soil.
Methods for Cleanup: Contain and collect spillage with inert absorbent (sand, earth). Place in suitable chemical waste container for disposal. Wash spill area with water.
Other Measures: Report significant releases to appropriate authorities.
Precautions for Safe Handling: Avoid contact with skin and eyes. Do not breathe vapor or mist. Use only with adequate ventilation. Wear suitable personal protective equipment.
Conditions for Safe Storage: Keep container tightly closed in a cool, dry, well-ventilated area. Store away from incompatible materials like strong oxidizers, acids, and bases. Protect from heat, sparks, and flame. Store in original container.
Specific Use(s): Ensure all local regulations concerning handling and storage are met.
Occupational Exposure Limits: Not established by OSHA, ACGIH or other agencies for MMA specifically.
Engineering Controls: General or local exhaust ventilation for indoor handling and transfer.
Personal Protective Equipment (PPE):
Gloves: Chemical-resistant (nitrile, neoprene);
Eye/face: Safety goggles or face shield;
Clothing: Lab coat or chemical-resistant apron;
Respiratory protection: If ventilation is inadequate, use organic vapor respirator.
Hygiene Measures: Wash hands after use, remove contaminated clothing before breaks and after work.
Appearance: Clear, colorless liquid
Odor: Mild, faint ester-like
Odor Threshold: Not determined
pH: Not available
Melting Point/Freezing Point: -15°C to -11°C
Boiling Point: 241°C at 760 mmHg
Flash Point: 112°C (closed cup)
Evaporation Rate: Not determined
Flammability: Not highly flammable but combustible
Upper/Lower Flammability or Explosive Limits: Not determined
Vapor Pressure: 0.035 mmHg at 25°C
Vapor Density: Heavier than air
Relative Density: ~1.09 (water = 1)
Solubility: Soluble in alcohol, partially soluble in water
Partition Coefficient (n-octanol/water): Not available
Auto-ignition Temperature: Not determined
Decomposition Temperature: Not available
Viscosity: Not available
Chemical Stability: Stable under normal storage and handling conditions.
Reactivity: No specific hazardous reactivity expected under recommended conditions.
Hazardous Reactions: Strong oxidizing agents, acids and bases may cause violent reactions.
Conditions to Avoid: Excessive heat, open flames, sparks, incompatibles.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide
Routes of Exposure: Inhalation, ingestion, skin contact, eye contact
Acute Toxicity: Low to moderate oral and dermal toxicity expected, based on structurally similar substances; oral LD50 (rat) >2000 mg/kg
Skin Corrosion/Irritation: Can cause skin irritation on prolonged or repeated exposure
Serious Eye Damage/Irritation: Causes moderate to severe eye irritation
Respiratory or Skin Sensitization: Not expected to be sensitizing
Germ Cell Mutagenicity: Data not available; no evidence from similar substances
Carcinogenicity: Not classified as carcinogen by IARC, NTP, OSHA
Reproductive Toxicity: No known adverse reproductive effects
Target Organ Effects: May cause irritation of respiratory system
Symptoms: Redness, pain, watery eyes, dry or cracked skin, coughing, sore throat on high exposure
Ecotoxicity: Slight hazard to aquatic organisms based on limited data for similar esters.
Aquatic Toxicity: LC50 (fish, 96h): >100 mg/L; EC50 (daphnia, 48h): >100 mg/L
Persistence and Degradability: Biodegradable under aerobic conditions
Bioaccumulative Potential: Low for bioaccumulation (estimated Log Kow <3)
Mobility in Soil: Moderately mobile, potential for groundwater contamination if released
Other Adverse Effects: Large spills may create oxygen depletion in water bodies
Waste Treatment Methods: Dispose of contents/container in accordance with local, regional, national, and international regulations
Product Disposal: Collect for incineration or disposal at properly permitted waste management facility
Container Disposal: Empty container should be triple rinsed, punctured, and offered for recycling or disposal; do not reuse containers
Special Precautions for Disposal: Avoid entry to waterways, inform authorities if large spill occurs
UN Number: Not regulated for transport
UN Proper Shipping Name: Not applicable
Transport Hazard Class: Not classified as hazardous for transportation under ADR, IMDG, IATA
Packing Group: Not applicable
Marine Pollutant: No
Special Precautions for User: Avoid temperature extremes during transport, secure containers to prevent leakage or breakage
TSCA Inventory: Listed
EINECS/ELINCS: Listed (210-555-8)
Japan ENCS: Listed
REACH Status: Registered or pre-registered
SARA Title III: Not subject to reporting under Sections 302, 304, 313
California Proposition 65: Not listed as a substance known to cause cancer or reproductive harm
Other Regulations: Check country-specific chemical control legislation for any restrictions
