Product Name: Hexadecanedioic Acid
Chemical Formula: C16H30O4
Synonyms: 1,16-Hexadecanedioic acid, Thapsic Acid, Hexadecandioic Acid
CAS Number: 505-49-7
Manufacturer: Industrial chemical suppliers, chemical laboratories, research entities
Use: Intermediate in chemical synthesis, specialty polymer production, pharmaceutical and cosmetic raw material
Contact Information: Emergency response contacts and manufacturer numbers displayed on the label and shipping documents
GHS Classification: Not classified as a hazardous substance or mixture
Physical Hazards: No significant reactivity hazard identified with normal handling
Health Hazards: Low acute toxicity, may cause mild irritation to eyes, skin, or respiratory system if dust generated and inhaled
Environmental Hazards: Limited evidence for aquatic or soil hazard; good manufacturing practice avoids excessive release
Label Elements: Pictograms usually not required; precautionary language for exposure may appear
Signal Word: None typically indicated for this chemical
Hazard Statements: May create dust that irritates, avoid contact with mucous membranes
Precautionary Statements: Avoid inhaling dust, wash hands after handling, use basic PPE in bulk handling scenarios
Chemical Identity: Hexadecanedioic Acid
CAS Number: 505-49-7
Concentration: Typically >98% as a pure compound
Impurities: Minor trace levels of related dicarboxylic acids or reaction byproducts can appear in technical grades, detailed on batch-specific COA
Stabilizing Additives: Not required, material stable under standard conditions
Other Ingredients: None intentionally present or required for function
Inhalation: Move affected person into fresh air, allow them to rest, seek care if irritation persists
Skin Contact: Wash contact area with soap and water, remove contaminated clothing
Eye Contact: Flush eyes thoroughly with clean water for several minutes, consult a doctor if irritation continues
Ingestion: Rinse mouth with water, do not induce vomiting, consult a physician if a large quantity has been swallowed
Note to Physician: Symptomatic treatment, no known specific antidote
Suitable Fire Extinguishing Media: Water spray, carbon dioxide, dry chemical, foam extinguishers
Specific Hazards: Dust from the product can form explosive mixtures with air in case of strong dispersion
Hazardous Combustion Products: Carbon monoxide, carbon dioxide, low molecular weight organic acids or vapors possible
Protective Equipment for Firefighters: Standard protective turnout gear, positive pressure self-contained breathing apparatus recommended
Additional Advice: Use caution with runoff from fire control which may be contaminated with residue from decomposition
Personal Precautions: Wear gloves, dust mask, and safety goggles for personal comfort
Environmental Precautions: Avoid direct discharge into sewers or waterways, gather up product for salvage or disposal
Methods for Cleaning Up: Sweep up spilled material with minimal dust generation, collect in suitable containers, ventilate area well if indoors
Reference to Other Sections: For personal protection and waste disposal refer to sections on PPE and disposal considerations
Decontamination: Wash spill area thoroughly after clean-up is finished
Safe Handling Recommendations: Use in a well-ventilated setting, avoid powdered dust clouds, avoid inhaling or contacting the material directly
Storage Conditions: Store in tightly closed containers in a cool, dry, and well-ventilated place
Keep Away From: Oxidizing agents, strong acids, strong bases
Packaging Materials: Use appropriate chemical-resistant packaging such as sealed high-density polyethylene containers or amber glass bottles as suitable for scale
General Hygiene: Practice standard hygiene, keep eating and drinking separate from work areas, wash hands after handling
Incompatibilities: Avoid contact with corrosive chemicals; keep away from high heat sources
Control Parameters: No established occupational exposure limits (OEL), exposure often limited by dust
Engineering Controls: Use local exhaust ventilation for dusty operations, general room ventilation for routine handling
Personal Protective Equipment: Gloves (nitrile or latex), chemical splash goggles, dust mask or respirator for bulk or dusty tasks, lab coat or protective garments
Respiratory Protection: Use a particulate respirator (N95 or P2) for high concentrations of airborne material
Eye/Face Protection: Wear safety goggles that provide dust protection
Skin Protection: Protective gloves, avoid repeated or prolonged contact with bare skin
Environmental Exposure Controls: Minimize spills and releases, follow industrial best practices to limit environmental impact
Appearance: White crystalline powder or fine solid
Odor: Odorless
pH: Not applicable in solid state; mildly acidic in aqueous suspension
Melting Point: Around 134–137°C
Boiling Point: Decomposes before boiling
Solubility (Water): Slightly soluble
Solubility (Other): More soluble in alcohols, acetone, and organic solvents
Density: About 1.2 g/cm³
Vapor Pressure: Negligible at room temperature
Partition Coefficient (log Kow): Estimated moderate
Flash Point: Not highly flammable, flash point data not widely established
Autoignition Temperature: Not typically a concern for this compound under normal handling
Chemical Stability: Stable under normal storage and handling conditions
Possibility of Hazardous Reactions: None expected in standard use
Conditions to Avoid: Excess heat, open flame, finely dispersed dust in confined spaces
Incompatible Materials: Strong oxidizing agents, strong bases, strong mineral acids
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, possibly irritating organic vapors in a fire or during prolonged severe heating
Routes of Exposure: Inhalation, skin contact, eye contact, accidental ingestion
Acute Effects: Mild irritation is possible through direct eye or skin contact or through inhalation of dust
Chronic Toxicity: Long-term harmful effects are not known or expected based on available data
Carcinogenicity: Not listed as a carcinogen by NTP, IARC, or OSHA
Mutagenicity: No evidence of genetic toxicity
Reproductive Toxicity: No evidence from animal or human studies
LD50 (oral, rat): Information not specifically determined but indicates low toxicity
Other Data: Care should be taken to avoid unnecessary exposure, especially for those sensitive to chemical dusts or acids
Aquatic Toxicity: Limited data suggest low toxicity to aquatic life at typical usage levels
Persistence and Degradability: Expected to biodegrade under typical environmental conditions, like most fatty acids
Bioaccumulative Potential: Not considered significant due to molecular structure
Mobility in Soil: Slight mobility, soil binding likely
Other Adverse Effects: Avoid direct release to natural water bodies, as with all organic process chemicals
Regulatory Statements: Standard industrial use set basic guidelines to prevent large spills into the environment
Disposal Methods: Dispose of in compliance with local, regional, and national regulations
Waste Treatment Options: Chemical waste incineration is efficient where permitted, landfill disposal in sealed containers where safe and authorized
Special Precautions: Avoid dispersal of dust into the air, avoid waterway contamination
Empty Packaging: Clean containers before recycling or reuse, dispose with chemical waste if contaminated
UN Number: Not regulated as a dangerous good for transport
Transport Hazard Class: Not classified
Packing Group: None
Environmental Hazards: Not known to present environmental risks on transport
Transport in Bulk: Follow separation precautions for powdered chemicals; no specific shipping restrictions
Special Precautions for Transport: Protect package from moisture and damage, use original packaging as labeled, comply with standard industry practices
Additional Labeling: None required beyond general chemical identification
OSHA Status: Not regulated as hazardous
TSCA Inventory: Listed
REACH Status: Registered or notified as relevant for EU commerce
Other International Inventories: Listed or exempt in many regulatory agency inventories worldwide
SARA Title III: Not subject to reporting requirements
California Prop 65: Not listed
WHMIS Classification: Non-controlled
Use Restrictions: Follow relevant safety and health guidelines for safe chemical handling
Further Regulatory Notes: Good record-keeping and workplace training ensure continued compliance and safety
