Histry Chem

Knowledge

MSDS (Material Safety Data Sheet) for Docosanol

Identification

Product Name: Docosanol
Chemical Name: 1-Docosanol
Synonyms: Behenyl alcohol
CAS Number: 661-19-8
Molecular Formula: C22H46O
Recommended Use: Pharmaceutical, topical antiviral
Manufacturer Details: Company address, contact phone number, email
Emergency Phone Number: Poison control or emergency services hotline

Hazard Identification

Classification: Not classified as hazardous under OSHA regulations
Signal Word: None required
Hazard Statements: Dust may cause mild eye or respiratory irritation
Pictograms: Not required
Precautionary Statements: Avoid contact with eyes, avoid inhaling dust, keep away from children
Potential Health Effects: Eye irritation, possible mild skin dryness, inhalation may cause coughing
Environmental Hazards: Not expected to produce significant environmental effects in small amounts

Composition / Information on Ingredients

Chemical: Docosanol
Concentration: >99%
CAS Number: 661-19-8
Impurities: May contain minimal long-chain alcohols as trace components
Additives: None

First Aid Measures

General Advice: Remove from area of exposure, seek fresh air
Inhalation: Move to fresh air, monitor for breathing difficulty, seek medical help if symptoms persist
Skin Contact: Wash thoroughly with soap and water; treat dryness with moisturizer
Eye Contact: Rinse eyes with water for several minutes, remove contact lenses if present, continue rinsing; doctor visit for irritation
Ingestion: Rinse mouth, drink water to dilute, observe for symptoms, seek medical advice if feeling unwell

Fire-Fighting Measures

Extinguishing Media: Use water spray, foam, dry chemical, or carbon dioxide
Fire Hazards: Combustible at elevated temperatures, may emit smoke or toxic fumes on burning
Firefighting Procedures: Wear self-contained breathing apparatus, keep upwind, use protective clothing
Special Equipment: Full firefighting gear, recommended to avoid exposure to fumes
Hazardous Combustion Products: Carbon monoxide, carbon dioxide, possible aldehydes

Accidental Release Measures

Personal Precautions: Avoid dust formation, use personal protective equipment
Environmental Precautions: Prevent runoff into waterways, avoid releasing into the environment
Cleanup Methods: Sweep or shovel spilled material, collect in compatible container, clean area with water; ventilate enclosed spaces
Disposal: Dispose of as nonhazardous waste in accordance with local, state, and federal regulations

Handling and Storage

Handling: Use with adequate ventilation, minimize dust generation, wash hands after handling
Storage Conditions: Store in tightly closed container, keep in cool, dry, well-ventilated area
Incompatibilities: Strong oxidizing agents
Container Requirements: Use corrosion-resistant, sealed containers
Special Precautions: Label containers properly, keep out of reach of children, avoid all unnecessary contact

Exposure Controls and Personal Protection

Occupational Exposure Limits: No specific values established
Engineering Controls: Provide local exhaust ventilation to minimize dust
Eye Protection: Safety goggles
Hand Protection: Chemical-resistant gloves
Skin Protection: Lab coat or chemical-resistant apron
Respiratory Protection: Use NIOSH-approved dust mask if ventilation is inadequate
Hygiene Measures: Wash hands thoroughly after handling, do not eat or drink in work area

Physical and Chemical Properties

Appearance: White, waxy solid
Odor: Slight, fatty odor
Odor Threshold: Not determined
pH: Not applicable
Melting Point: 74–79°C (165–174°F)
Boiling Point: 305°C
Flash Point: >150°C (open cup)
Evaporation Rate: Not applicable
Flammability: Not classified as highly flammable
Vapor Pressure: <0.01 mmHg at 25°C
Vapor Density: Not determined
Relative Density: 0.82–0.85 g/cm³
Solubility: Practically insoluble in water, soluble in alcohols and oils
Partition Coefficient: log Kow >6
Auto-Ignition Temperature: Not determined
Decomposition Temperature: Not determined
Viscosity: Not applicable

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions
Reactivity: No known reactivity hazards
Possibility of Hazardous Reactions: None expected
Conditions to Avoid: Open flames, extreme heat, strong oxidizers
Incompatible Materials: Strong oxidizing agents
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, possibly irritating smoke

Toxicological Information

Routes of Exposure: Inhalation, skin, eyes, ingestion
Acute Toxicity: Low toxicity, large doses may cause minor gastrointestinal upset
Skin Corrosion/Irritation: Mild drying possible on prolonged contact
Serious Eye Damage/Irritation: Mild, reversible irritation
Respiratory Effects: Mild, transient irritation possible from dust
Sensitization: Not a known sensitizer
Repeated Dose Toxicity: No evidence of organ toxicity from chronic exposure
Carcinogenicity: Not listed as a carcinogen by IARC, NTP, OSHA
Mutagenicity: Not mutagenic in standard assays
Reproductive Toxicity: No adverse effects reported

Ecological Information

Ecotoxicity: Not expected to be harmful to aquatic life in small quantities
Persistence and Degradability: Biodegradable, breaks down in the environment
Bioaccumulative Potential: High log Kow suggests possible bioaccumulation, but rapid degradation reduces risk
Mobility in Soil: Limited; binds to soil particles
Other Adverse Effects: No significant impacts reported with customary use and disposal

Disposal Considerations

Waste Disposal Methods: Dispose in accordance with local, regional, and national regulations
Packaging Disposal: Empty containers should be taken to local recycling, reusing in compatible settings where possible
Special Precautions for Landfills: Avoid dumping in open landfills or water systems, minimize environmental exposure
Incineration: Material can be incinerated in accordance with regulations

Transport Information

UN Number: Not regulated
UN Proper Shipping Name: Not applicable
Transport Hazard Class: Non-hazardous
Packing Group: Not classified
Marine Pollutant: No
Special Precautions for User: Handle with care to prevent spills and dust
Transport Label Requirements: Ordinary shipment, no special placarding necessary

Regulatory Information

OSHA: Not classified as hazardous
TSCA Status: Listed in TSCA Inventory
SARA Title III: Not subject to reporting under Sections 311/312/313
DSL Status (Canada): Listed
EU REACH: Registered
Labeling Requirements: Standard non-hazardous labeling as per applicable jurisdiction
Other: No specific restrictions on use under normal industrial or consumer use