Product Name: Dimethyl Glutarate
Synonyms: Glutaric acid dimethyl ester
CAS Number: 1119-40-0
Recommended Use: Solvent, chemical intermediate, cleaning agent
Supplier Information: Chemical manufacturer details, address, emergency contact number
Emergency Telephone: Chemtrec (24-hour assistance)
Relevant Identified Uses: Intermediate in industrial synthesis, component in specialty coatings
GHS Classification: Eye irritation category 2A, skin irritation category 2, specific target organ toxicity (single exposure) category 3
Label Elements: Signal word: Warning, exclamation mark pictogram
Hazard Statements: Causes skin and serious eye irritation, may cause respiratory irritation
Precautionary Statements: Wear protective gloves and eye protection, avoid breathing dust or vapor, wash thoroughly after handling
Routes of Exposure: Inhalation, skin contact, eye contact, ingestion
Other Hazards: May cause mild central nervous system effects at high concentrations
Chemical Name: Dimethyl Glutarate
Concentration/Range: >98%
CAS Number: 1119-40-0
Impurities: Trace amounts of related esters (Dimethyl adipate, dimethyl succinate may occur in commercial formulations)
Inhalation: Move exposed person to fresh air, keep comfortable for breathing, seek medical attention if symptoms persist
Skin contact: Take off contaminated clothing, wash skin with soap and water, contact physician if irritation remains
Eye contact: Rinse cautiously with water for several minutes, remove contact lenses if present, continue rinsing, consult doctor if irritation lingers
Ingestion: Rinse mouth, do not induce vomiting, seek immediate medical assistance for large amounts ingested or symptoms
Acute Symptoms: Eye redness, burning, coughing, skin irritation, light-headedness after significant inhalation exposure
Suitable Extinguishing Media: Carbon dioxide, dry chemical powder, alcohol-resistant foam
Hazards from Combustion: Emits toxic fumes such as carbon monoxide and carbon dioxide in fire
Protective Equipment: Full-face self-contained breathing apparatus, flame-resistant protective clothing
Special Procedures: Cool fire-exposed containers with water spray, stay upwind to avoid inhalation of combustion products
Flammability: Liquid combustible at high temperatures; flash point approximately 97°C (207°F)
Personal Precautions: Wear recommended protective equipment including gloves, safety goggles, chemical-resistant apron
Spill Cleanup: Absorb with inert material (e.g. sand), collect in labeled containers, ventilate spill area
Environmental Precautions: Prevent runoff into drains, waterways, soil; notify authorities if significant release occurs
Disposal: Dispose soaked materials in accordance with local, regional, and national regulations for hazardous waste
Handling: Use in a ventilated area, avoid inhaling vapors, prevent contact with skin and eyes, avoid eating or smoking
Storage Conditions: Store tightly sealed in a cool, dry, well-ventilated location away from incompatible materials
Incompatibles: Strong acids, alkalies, oxidizing agents
Special Considerations: Use non-sparking tools, keep away from ignition sources, ensure containers remain labeled and upright
Engineering Controls: Provide local exhaust or general ventilation to minimize exposure
Personal Protective Equipment: Chemical-resistant gloves (such as nitrile), safety glasses with side shields or goggles, laboratory coat or apron, use an approved organic vapor respirator if workplace concentrations exceed defined limits
Occupational Exposure Limits: None established by OSHA, NIOSH, or ACGIH for Dimethyl Glutarate
Hygiene Measures: Wash hands thoroughly before breaks and at end of workday, avoid continued skin contact
Physical State: Clear, colorless to pale yellow liquid
Odor: Mild, ester-like fragrance
Boiling Point: Approx. 196°C (384°F)
Melting Point: -40°C (-40°F)
Density: About 1.11 g/cm³ at 20°C
Vapor Pressure: Low, around 0.2 hPa at 20°C
Solubility: Limited in water, miscible with organic solvents
Viscosity: 1.63 mPa·s at 25°C
Flash Point: ~97°C (207°F)
pH: Not applicable (non-aqueous liquid)
Partition Coefficient (Octanol/Water): log Kow ≈ 0.6
Auto-ignition Temperature: 433°C (811°F)
Chemical Stability: Stable under recommended storage conditions
Hazardous Reactions: None reported under normal conditions
Materials to Avoid: Strong oxidizers, acids, alkalies
Decomposition Products: May release toxic vapors of carbon oxides on thermal breakdown
Polymerization: Does not occur in normal use
Environmental Influence: Product is volatile at elevated temperatures, avoid vapor accumulation
Likely Routes of Exposure: Inhalation, skin and eye contact, ingestion
Acute Toxicity: Low acute toxicity; LD50 oral (rat): 8191 mg/kg; LD50 dermal (rabbit): >2000 mg/kg
Irritation/Corrosiveness: Can cause moderate to strong irritation to eyes, mild to moderate skin irritation
Sensitization: Not known to cause allergic skin reaction
Chronic Effects: Repeated exposure may lead to dryness or cracking of skin, mild respiratory tract irritation
Carcinogenicity: Not classified by IARC, NTP, or OSHA
Reproductive Toxicity: No evidence known. No data indicating reproductive effects
Other Effects: Headache, dizziness, fatigue possibly observed after inhalation in poorly ventilated settings
Aquatic Toxicity: LC50 (fish, 96 h): 120 mg/L (Pimephales promelas)
Biodegradability: Readily biodegradable as per OECD 301C method
Bioaccumulative Potential: Log Kow suggests low potential for bioaccumulation
Mobility in Soil: Leaches slowly, does not persist in environment, mobile in water
Other Adverse Effects: No evidence of toxicity to birds or soil organisms at relevant concentrations
Waste Disposal Methods: Dispose through licensed chemical waste contractor, follow federal, state, and local regulations
Contaminated Packaging: Empty containers must be triple-rinsed and sent for recycling or incineration, do not reuse containers for other purposes
Special Instructions: Avoid release to environment, do not pour down drains, absorption onto inert material for large spill handling strongly recommended
UN Number: Not regulated by DOT, IMDG, or IATA for transportation
Proper Shipping Name: Not classified as a dangerous good for transport
Hazard Class: None assigned
Packing Group: None required
Special Precautions: Keep containers upright, ensure lids are tight, transport in original packaging when practical, avoid loading with strong oxidizers or acids
Inventory Status: Listed on TSCA inventory (USA), EINECS (Europe), DSL (Canada)
SARA Title III: Not a regulated substance under Sections 302, 304, 313
OSHA Hazard Communication: Classified as hazardous based on eye and skin irritant properties
California Proposition 65: Substance not listed
Other Regulations: Compliant with REACH registration, not subject to PICCS, ENCS, or AICS restrictions
Label Requirements: Conform to GHS pictogram and labeling as per OSHA 29 CFR 1910.1200 regulation
