Product Name: Caprolactone Monomer
Chemical Name: ε-Caprolactone
Synonyms: 1,6-Hexanolactone; Hexan-6-olide
CAS Number: 502-44-3
Recommended Use: Chemical intermediate for production of polymers
Manufacturer: Refer to supplier information and emergency contact
Emergency Phone Number: Local Poison Center or emergency number
GHS Classification: Skin Irritant (Category 2), Eye Irritant (Category 2A), Acute Toxicity Oral (Category 4)
Signal Word: Warning
Hazard Statements: Causes skin irritation, causes serious eye irritation, harmful if swallowed
Pictograms: Exclamation mark symbol
Precautionary Statements: Avoid contact with eyes, skin, and clothing. Wash hands thoroughly after handling. Do not eat, drink, or smoke when using this product.
Component: Caprolactone Monomer
Concentration: ≥ 99%
Chemical Formula: C6H10O2
Impurities: Residual solvents, trace water, and byproducts may be present in very low concentrations, with specific content subject to supplier technical data
Inhalation: Move person to fresh air. Get medical attention if symptoms develop or persist.
Skin Contact: Remove contaminated clothing, rinse skin with plenty of water for at least 15 minutes. Seek medical advice for persistent irritation.
Eye Contact: Flush eyes with water for at least 15 minutes, lifting eyelids occasionally. Immediate medical attention often proves necessary.
Ingestion: Rinse mouth with water, do not induce vomiting unless directed by medical personnel. Get medical help right away.
Suitable Extinguishing Media: Dry chemical powder, carbon dioxide, alcohol-resistant foam, water spray used for larger fires
Hazards from Combustion: Produces carbon monoxide, carbon dioxide, and other toxic fumes under fire
Protective Equipment: Firefighters wear self-contained breathing apparatus and full protective gear
Advice for Firefighters: Move containers from fire area if safe to do so. Cool exposed containers with water spray to prevent rupture.
Personal Precautions: Evacuate unnecessary personnel, ventilate area, avoid breathing vapors, provide suitable personal protective equipment
Environmental Precautions: Contain spill, prevent from entering drains and waterways
Cleanup Methods: Absorb with inert material (sand, earth, vermiculite), place in chemical waste container for disposal
Decontamination: Wash area with water and detergent
Safe Handling: Handle in a well-ventilated area, avoid contact with skin and eyes, avoid inhaling vapors
Storage Conditions: Store in tightly closed container in a cool, dry, well-ventilated place away from heat sources, oxidizers, acids, and bases
Incompatibilities: Avoid strong acids, strong bases, and oxidizing agents
Special Precautions: Use non-sparking tools, keep away from open flame or hot surfaces
Occupational Exposure Limits: No established exposure limits for caprolactone. Work practices should minimize exposure.
Ventilation: Use local exhaust ventilation or process enclosure to capture vapor or mist
Respiratory Protection: Use NIOSH-approved respirator if ventilation is inadequate
Hand Protection: Chemical-resistant gloves (e.g., nitrile, neoprene)
Eye/Face Protection: Safety goggles or face shield
Skin Protection: Protective clothing such as lab coat, long sleeves
General Hygiene: Wash thoroughly after handling, remove contaminated clothing, and wash before reuse
Appearance: Colorless to pale yellow liquid
Odor: Mild, characteristic odor
Odor Threshold: Not available
pH: Not applicable
Melting Point: −1.3 °C (30.7 °F)
Boiling Point: 239 °C (462 °F)
Flash Point: 113 °C (235 °F) (closed cup)
Evaporation Rate: Not determined
Flammability: Not classified as flammable but can burn above flash point
Vapor Pressure: 0.2 mmHg at 25 °C
Vapor Density: 4.2 (air = 1)
Relative Density: About 1.07 g/cm³ at 20 °C
Solubility: Slightly soluble in water, miscible with most organic solvents
Partition Coefficient (n-octanol/water): 0.68
Auto-Ignition Temperature: 320 °C (608 °F)
Decomposition Temperature: Not determined
Viscosity: 2.25 mPa·s at 25 °C
Chemical Stability: Caprolactone monomer stays stable under recommended storage conditions
Reactivity: Typically unreactive, can react with strong acids, bases, and oxidizers
Hazardous Reactions: Polymerization may occur if contaminated by moisture, amines, or basic materials
Conditions to Avoid: Heat, flames, ignition sources, prolonged exposure to air or moisture
Incompatible Materials: Avoid alkali, strong acids, oxidizers, alcohols and amines
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, fumes
Acute Toxicity: Oral LD50 (rat) about 3800 mg/kg; low toxicity by inhalation or dermal exposure
Skin Corrosion/Irritation: Can cause irritation with prolonged exposure
Eye Damage/Irritation: Causes moderate to severe irritation
Respiratory or Skin Sensitization: Not considered a sensitizer
Chronic Toxicity: No evidence of chronic effects in industrial exposures
Carcinogenicity: Not listed as carcinogenic by IARC, NTP, or OSHA
Specific Target Organ Toxicity: Not expected to result in target organ toxicity
Potential Health Effects: Ingestion may cause nausea, vomiting, abdominal pain; skin contact may result in redness and irritation; vapor or mist inhalation may irritate respiratory system
Ecotoxicity: Not classified as hazardous to aquatic life according to current regulations
Persistence and Degradability: Biodegrades in environment, forms CO2 and water as major products
Bioaccumulative Potential: Low; log Kow suggests low potential for bioaccumulation
Mobility in Soil: Moderate mobility, may partition into water and soil
Other Adverse Effects: Avoid release to environment, spills can harm aquatic organisms in high concentrations
Waste Disposal Methods: Dispose of according to local, regional, and national regulations; incineration or chemical treatment preferred
Packaging Disposal: Drums, bottles, or inner containers that hold residues should be drained and triple-rinsed, then offered for recycling or incineration
Contaminated Materials: Handle as hazardous waste
Precautions: Do not allow product to enter drains or watercourses
UN Number: Not regulated as dangerous goods for transport
Proper Shipping Name: Caprolactone Monomer, not classified as hazardous
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Environmental Hazards: Not classified as environmentally hazardous under transport regulations
Transportation Precautions: Keep container tightly closed, transported upright, segregate from strong oxidizers and incompatible materials
TSCA Status: Caprolactone included on the inventory
REACH Status: Registered in accordance with EU regulations
SARA Title III: Not considered a hazardous substance under Sections 302, 311, 312, 313
California Proposition 65: Not listed
Other International Regulations: Refer to national chemical inventories and workplace regulations for additional compliance and restrictions
Workplace Labeling Requirements: Ensure all secondary containers display compliant and updated safety information
