Product Name: Azelaic Acid
Chemical Formula: C9H16O4
CAS Number: 123-99-9
Synonyms: Nonanedioic Acid
Recommended Use: Skin-conditioning agent in pharmaceuticals, topical treatments in dermatology, industrial applications in polymer production
Supplier Contact: Details required from the distributing company for safety and emergency information
Emergency Phone Number: Provided by local safety authorities or supplier
GHS Classification: Eye irritation (category 2A), Skin irritation (category 2)
Pictogram: Exclamation mark
Signal Word: Warning
Hazard Statements: Causes skin and eye irritation, Possible respiratory tract irritation
Precautionary Statements: Avoid inhalation of dust, Prevent contact with skin and eyes, Wear protective clothing and gloves, Wash thoroughly after handling
Potential Health Effects: Redness and mild allergic reactions on sensitive individual’s skin; coughing, or wheezing if dust inhaled
Environmental Impact: Harmful to aquatic life if released in significant quantities
Chemical Name: Azelaic Acid
Concentration: >99% pure
Impurities: Minimal, often less than 0.5% total
Molecular Mass: 188.22 g/mol
Eye Contact: Flush immediately with plenty of clean water for at least 15 minutes, Remove contact lenses if present
Skin Contact: Wash affected area with soap and water; Remove contaminated clothing and wash before reuse
Inhalation: Move exposed person to fresh air, Seek medical attention if symptoms persist
Ingestion: Rinse mouth with water; drink water in small sips, Do not induce vomiting unless advised by medical personnel
Suitable Extinguishing Media: Dry chemical, foam, water spray, or carbon dioxide
Fire Hazards: Dust from product can form explosive mixtures with air, May emit toxic fumes such as carbon oxides on burning
Protective Equipment: Firefighters should wear full protective clothing and self-contained breathing apparatus
Special Procedures: Approach fire from upwind to avoid hazardous vapors and decomposition products
Unsuitable Extinguishing Methods: Avoid direct water stream as it may spread burning material
Personal Precautions: Wear gloves, goggles, dust mask, Avoid breathing dust
Environmental Precautions: Prevent entry into water sources and drains
Methods for Cleaning Up: Sweep up with care to avoid dust formation, Collect in suitable closed and labeled containers, Clean area with plenty of water after collection, Dispose following local regulations regarding chemical waste
Handling: Keep containers tightly closed, Use only in well-ventilated areas, Avoid contact with skin, eyes, and clothing, Do not eat, drink, or smoke during use, Wash hands after handling
Storage: Store in a cool, dry place away from direct sunlight and incompatible materials such as strong oxidizers, Keep storage temperature below 25°C, Protect from moisture, Store in general chemical area with appropriate labeling
Engineering Controls: Local and general ventilation recommended to control airborne particulates, Use fume hoods where dust or vapors are present
Personal Protection: Safety goggles or face shield to protect eyes, Gloves impervious to chemicals, Protective lab coat or apron, Respiratory protection in areas with inadequate ventilation
Hygiene Measures: Do not touch face or wipe eyes during use, Change contaminated clothing promptly, Wash exposed skin after handling
Appearance: White crystalline powder
Odor: Neutral to faint fatty odor
Melting Point: 105–111°C
Boiling Point: 286°C at 760 mmHg
Solubility: Sparingly soluble in cold water, freely soluble in hot water and alcohol
pH: 4.5–6 (1% solution in water)
Vapor Pressure: Negligible at room temperature
Density: 1.22 g/cm³ at 20°C
Partition Coefficient (n-octanol/water): log Pow ≈ -0.24
Chemical Stability: Stable at recommended storage temperature
Reactivity: May react with strong oxidizers, Avoid elevated heat
Decomposition Products: Carbon monoxide, carbon dioxide, low amounts of organic acids
Incompatible Materials: Strong bases, oxidizing agents
Oral LD50 (rat): > 5,000 mg/kg
Dermal LD50 (rabbit): > 2,000 mg/kg
Acute Effects: Mild skin and eye irritation, low oral toxicity
Chronic Effects: Prolonged exposure may result in dryness or cracking of skin
Sensitization: Rare, but not impossible in susceptible individuals
Mutagenicity / Carcinogenicity: Tests show no evidence of mutagenic or carcinogenic potential
Acute Aquatic Toxicity: Slightly toxic to aquatic organisms
Persistence and Degradability: Biodegradable in the environment
Bioaccumulation Potential: Low potential based on log Pow
Mobility in Soil: Moderate solubility, possible movement in soil to water sources
Other Adverse Effects: Significant spills may reduce oxygen in aquatic systems due to microbial degradation
Waste Treatment Methods: Collect and place in tightly sealed containers, Follow local hazardous waste regulations for chemical disposal
Contaminated Packaging: Clean containers with thorough washing before recycling or disposal, Dispose of containers in accordance with local laws
Precautions: Do not dispose into drains or the environment
UN Number: Not classified as dangerous goods by transport regulations
Proper Shipping Name: Azelaic Acid
Transport Hazard Class: Non-regulated
Packing Group: Not assigned
Special Precautions: Avoid situations where packaging might rupture to prevent dust inhalation during transport
EU Regulations: Listed under REACH, not considered dangerous under CLP
United States Regulations: Listed on TSCA Inventory, not classified as hazardous under OSHA
Other International Listings: Included on Canadian DSL/NDSL, AICS (Australia), NZIoC (New Zealand), and other international inventories
Workplace Categorization: May require workplace labeling and exposure monitoring based on amount and usage scenario
