Product Name: 2-Butyne-1,4-Diol
Synonyms: 1,4-Butynediol; BYD
CAS Number: 110-65-6
Recommended Use: Intermediate for organic synthesis, production of plastics, pharmaceuticals, and agrochemicals
Manufacturer: Identify company with contact details and emergency phone numbers available 24/7
Emergency Overview: Flammable, toxic if swallowed, causes burns to skin and eyes
Classification: Acute toxicity (oral, dermal, inhalation), skin corrosion/irritation, serious eye damage/irritation, specific target organ toxicity single exposure, flammable liquid
Hazard Statements: Harmful if swallowed, toxic in contact with skin, causes severe skin burns and eye damage, may cause respiratory irritation, flammable liquid and vapor
Signal Word: Danger
Pictograms: Corrosive, Health hazard, Exclamation mark, Flame
Precautionary Statements: Avoid all contact with skin, eyes, and clothing. Wash hands thoroughly after handling. Use only outdoors or in a well-ventilated area. Wear appropriate personal protective equipment.
Chemical Name: 2-Butyne-1,4-Diol
CAS Number: 110-65-6
Concentration: >99% (technical grade)
Impurities: Trace amounts of water or other related butyne diols possible. No significant additives or stabilizers reported.
General Advice: Move victim away from source of exposure. Seek immediate medical attention if symptoms develop.
Inhalation: Remove person to fresh air. Keep victim at rest. Get medical attention for respiratory symptoms.
Skin Contact: Immediately take off contaminated clothing. Rinse skin with plenty of water for at least 15 minutes. Use soap if possible. Seek medical help for burns or persistent pain.
Eye Contact: Rinse cautiously with water for several minutes, lifting eyelids occasionally. Remove contact lenses if present and easy to do. Continue rinsing and seek urgent medical care.
Ingestion: Do not induce vomiting. Rinse mouth. Give water to drink if the person is conscious. Get medical help without delay.
Most Important Symptoms: Skin, respiratory and eye irritation or burns; difficulty breathing; possible delayed effects involving the nervous system or organs
Suitable Extinguishing Media: Use alcohol-resistant foam, dry chemical powder, or carbon dioxide. Water spray for larger fires to cool containers.
Specific Hazards: Vapors may form explosive mixtures with air. Combustion may release toxic gases such as carbon monoxide and carbon dioxide.
Protective Equipment and Precautions: Firefighters must wear full protective clothing including self-contained breathing apparatus. Containers exposed to fire may rupture. Cool containers with water spray to prevent pressure buildup.
Special Remarks: Approach upwind. Do not allow run-off from firefighting to enter drains or waterways.
Personal Precautions: Evacuate area. Avoid breathing vapors or mist. Remove all sources of ignition. Use personal protective equipment including gloves, goggles, and protective clothing.
Environmental Precautions: Prevent spillage from entering drains, surface water, or soil. Notify environmental authorities if contamination occurs.
Methods for Clean-Up: Absorb with inert material (such as dry sand or earth). Place in chemical waste container for disposal. Ventilate area. Wash spill site after material pick-up is complete.
Safe Handling: Only handle with adequate ventilation. Avoid skin, eye, and clothing contact. Never add water directly into the container. Wash hands after handling. Keep containers tightly closed.
Storage Conditions: Store in a cool, dry, well-ventilated area away from heat sources, sparks, and open flames. Separate from oxidizers, acids, and bases. Store in original packaging or compatible storage containers.
Incompatible Materials: Protect from strong acids, bases, oxidizing agents, and reducing agents that could trigger hazardous reactions.
Special Requirements: Maintain proper labeling. Keep emergency showers and eyewash stations accessible.
Occupational Exposure Limits: No established OSHA PEL or ACGIH TLV. Use the lowest feasible exposure levels.
Engineering Controls: Use local exhaust ventilation. Install safety showers and eye wash stations. Monitor vapor levels in air.
Personal Protection: Wear chemical-resistant gloves (nitrile or neoprene), protective clothing, safety goggles or face shields, and suitable respiratory protection for vapor/mists.
Hygiene Measures: Do not eat, drink, or smoke during use. Remove contaminated clothing and wash prior to reuse.
Appearance: Colorless to pale yellow liquid
Odor: Faint, sweetish odor
Melting Point: 16-20 °C
Boiling Point: 235-238 °C at 760 mmHg
Flash Point: 104 °C (closed cup)
Auto-ignition Temperature: 380 °C
Flammability: Flammable liquid
Vapor Pressure: 0.09 mbar at 25 °C
Solubility: Soluble in water, alcohol, and ether
Density: 1.06 g/cm3 (20 °C)
pH: Not applicable (neutral molecule)
Partition Coefficient (log Kow): -0.7 (estimated)
Viscosity: Not determined
Chemical Stability: Stable under recommended storage and handling conditions.
Reactivity: Reacts with strong acids, bases, oxidizers, and reducing agents.
Hazardous Reactions: Risk of violent reaction or decomposition if mixed with incompatible materials.
Decomposition Products: Generates toxic/corrosive gases such as carbon monoxide and carbon dioxide on thermal decomposition.
Conditions to Avoid: Heat, flames, ignition sources; avoid direct sunlight and moisture.
Acute Toxicity: Oral LD50 (rats): 132 mg/kg; Dermal LD50 (rabbits): 398 mg/kg. Causes severe burns in eyes, skin, and respiratory tract.
Chronic Effects: Potential systemic effects after prolonged exposure include nervous system and organ damage.
Routes of Exposure: Inhalation, ingestion, dermal and ocular contact.
Symptoms: Burning sensation, cough, abdominal pain, shock, blurred vision, unconsciousness with high exposures.
Carcinogenicity: Not classified as carcinogenic by IARC/ACGIH/OSHA.
Mutagenicity/Teratogenicity: No evidence provided in animal studies; avoid unnecessary exposure during pregnancy.
Other Information: Repeated or long-term exposures increase risk of organ or nervous system effects.
Ecotoxicity: Harmful to aquatic organisms. May cause long-term adverse effects in the aquatic environment.
Persistence and Degradability: Expected to be biodegradable but persisting at high concentrations in water and soil for periods.
Bioaccumulation: Low potential due to low log Kow.
Mobility in Soil: High solubility in water points to high mobility in soils and potential to enter groundwater.
Other Adverse Effects: Local aquatic life at risk in event of spillage; avoid discharge to environment.
Waste Methods: Must follow local, regional, and national laws for hazardous waste. Dispose of residue and contaminated materials in sealed, labeled, chemical waste containers.
Contaminated Packaging: Empty containers must be rinsed and disposed of as hazardous waste.
Special Precautions: Do not discharge to drains or environment. Use authorized waste disposal contractors who understand risks of butynediol substances.
UN Number: UN 2810
Proper Shipping Name: Toxic Liquid, Organic, N.O.S. (2-Butyne-1,4-Diol)
Hazard Class: 6.1 (Toxic Substances)
Packing Group: II
Environmental Hazards: Harmful to aquatic life if spilled
Transport Labels: Toxic, Flammable Liquid
Additional Information: Transport in accordance with local/national/international regulations ensuring all risk management for flammable/toxic cargo.
OSHA: Hazardous Chemical per OSHA Hazard Communication Standard.
TSCA: Listed on U.S. Toxic Substances Control Act Inventory.
SARA Title III: Not categorized under Extremely Hazardous Substances. Section 313 listing depending on concentration/usage.
REACH: Registered substance in accordance with European regulations.
Canadian WHMIS: Classified as Class B2 (Flammable Liquid), D1B (Toxic), E (Corrosive) substance.
State Regulations: May be listed under state right-to-know laws (California Prop 65, New Jersey, Pennsylvania, etc).
Other Information: Workers must receive training and information about hazards, handling, and emergency procedures.
