Substance Name: 1-Octanol
Chemical Formula: C8H18O
Synonyms: Capryl alcohol, Octyl alcohol, n-Octanol
CAS Number: 111-87-5
Use: Solvent, fragrance ingredient, intermediate for plasticizers and surfactants, used in flavors and industrial applications
Manufacturer: Chemical supply and manufacturing firms, labs, distributors
Classification: Causes skin and eye irritation; harmful if swallowed; may cause respiratory irritation
GHS Label Elements: Exclamation mark (irritant)
Precautionary Statements: Avoid contact with skin or eyes, prevent inhalation of vapors, keep away from food and drink, wash hands thoroughly after handling
Potential Health Effects: Skin redness, discomfort to eyes, headache, dizziness upon high inhalation, abdominal pain if ingested
Chemical Name: 1-Octanol
Purity: Typically 98% or higher
CAS Registry Number: 111-87-5
Impurities: May contain other structurally similar alcohols at low concentrations due to synthesis routes
Inhalation: Move person to fresh air, provide oxygen or artificial respiration if breathing is difficult, seek medical attention if symptoms persist
Skin Contact: Remove contaminated clothing, rinse skin thoroughly with soap and water for at least 15 minutes, consult a physician if irritation continues
Eye Contact: Flush eyes with water for at least 15 minutes, hold eyelids open and seek medical help immediately
Ingestion: Rinse mouth, do not induce vomiting, seek professional medical care without delay
Notes to Physician: Treat symptomatically; consider gastric lavage for large volume exposures, monitor for aspiration pneumonia
Flammability: Flammable liquid
Suitable Extinguishing Media: Alcohol-resistant foam, dry chemical powder, carbon dioxide
Unsuitable Media: Water jets or streams may spread fire
Specific Hazards: Vapors may form explosive mixtures with air, fumes can be toxic
Protective Equipment: Full firefighting gear, self-contained breathing apparatus
Advice for Firefighters: Move containers from fire area if possible, cool with water spray, stay upwind, keep away from ignition sources
Personal Precautions: Use protective gloves, safety goggles, avoid breathing vapors, ventilate area
Environmental Precautions: Prevent entry to sewers, surface water, soil; build dikes if necessary
Methods for Containment: Absorb with inert material (sand, earth, vermiculite), collect in closed containers for proper disposal, clean spill area with detergent and water
Emergency Procedures: Evacuate non-essential personnel, provide adequate ventilation
Precautions for Safe Handling: Wear appropriate PPE, prevent skin and eye contact, avoid inhaling vapor or mist, use only in well-ventilated areas, keep away from heat and ignition sources
Storage Conditions: Store in tightly closed containers, keep in cool, well-ventilated place, separate from oxidizers and strong acids, protect from sunlight and moisture
Incompatibilities: Strong oxidizing agents, strong acids, alkali metals
Engineering Controls: Use local exhaust ventilation, enclose processes where feasible, prevent vapor accumulation
Personal Protective Equipment (PPE): Impervious gloves (nitrile, neoprene), chemical safety goggles, face shield for large volumes, lab coat or apron, respiratory protection if vapor concentration exceeds limits
Exposure Limits: No specific OSHA or ACGIH limits; minimize exposure and keep airborne concentrations as low as possible
General Hygiene: Wash hands after handling, do not eat or drink near product, remove contaminated clothing
Appearance: Colorless to pale yellow liquid
Odor: Faint oily, floral odor
Molecular Weight: 130.23 g/mol
Melting Point: Approximately -15°C
Boiling Point: 194°C
Flash Point: 81°C (closed cup)
Explosive Limits: Lower: 0.9%; Upper: data not available
Solubility: Slightly soluble in water, fully miscible with most organic solvents
Vapor Pressure: 0.13 mmHg at 20°C
Density: 0.826 g/cm³ at 20°C
Viscosity: 9.26 mPa·s at 25°C
Chemical Stability: Stable under recommended storage and handling conditions
Conditions to Avoid: Excessive heat, open flames, sources of ignition
Materials to Avoid: Oxidizers, strong acids, alkali metals
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, and potentially irritating fumes
Polymerization: Product does not undergo hazardous polymerization
Likely Routes of Exposure: Inhalation, ingestion, dermal contact, eye contact
Acute Toxicity: Oral LD50 (rat): 1790 mg/kg, Dermal LD50 (rabbit): > 3200 mg/kg
Skin & Eye Irritation: Moderate skin irritant, strong eye irritant
Symptoms: Dyspnea, headache, drowsiness, nausea, vomiting, eye and skin redness, discomfort
Chronic Effects: Prolonged exposure may affect liver and kidneys, repeated contact may defat skin
Carcinogenicity: Not listed as carcinogenic by IARC, NTP, OSHA
Mutagenicity/Reproductive Toxicity: No reports of mutagenic or reproductive effects in available data
Ecotoxicity: Slightly toxic to aquatic organisms; fish LC50 (96h): ~ 17 mg/L (Pimephales promelas)
Persistence and Degradability: 1-Octanol is inherently biodegradable, expected to degrade in the environment under aerobic conditions
Bioaccumulative Potential: Potential to bioaccumulate is moderate due to its log Kow of ~3
Mobility in Soil: Has moderate mobility, likely to partition to soil and sediment
Other Adverse Effects: Avoid large spills due to potential for localized environmental harm
Waste Treatment Methods: Dispose of spilled or unused material in accordance with local, regional, national, and international regulations, do not pour into drains or natural waters
Contaminated Packaging: Rinse containers, offer for recycling if available, otherwise dispose with hazardous chemical waste
Handling of Waste: Use licensed waste contractor, store waste in labeled, sealed containers
UN Number: 1993 (if regulated as a flammable liquid)
Proper Shipping Name: Flammable Liquid, N.O.S. (contains 1-Octanol)
Transport Hazard Class: 3 (Flammable liquid)
Packing Group: III
Environmental Hazards: Not regulated as marine pollutant
Special Transport Precautions: Secure tightly, keep away from heat sources, ensure correct labelling during transit
US Regulations: Listed under TSCA inventory, not a hazardous substance under CERCLA
EU Regulations: Listed under REACH, subject to requirements for registration and safety assessment
Canada: Listed on DSL/NDSL
Other International: Inventory listed in countries including Australia (AICS), Japan (ENCS), Philippines (PICCS)
Labelling Required: Hazard symbol for irritant, flammable liquid, precautionary statements for safe use
