Product Name: 1,2-Hexanediol
Chemical formula: C6H14O2
CAS Number: 6920-22-5
Synonyms: Hexane-1,2-diol, 1,2-Dihydroxyhexane
Product Use: Used as a solvent, wetting agent, and preservative in cosmetics, household products, and certain industrial applications.
Manufacturer/Supplier: Not applicable; refer to specific procurement channel.
Emergency Phone Number: Local poison control center or manufacturer’s emergency contact.
Classification: Not classified as hazardous under most global GHS standards. May cause mild irritation to eyes, skin, and respiratory tract.
Signal Word: Warning
Hazard Statements: Causes mild skin and eye irritation, avoid inhaling vapors and contact with eyes, skin, and clothing.
Precautionary Statements: Wash thoroughly after handling. Wear protective gloves and eye protection. Use only outdoors or in well-ventilated area.
Symptoms: Redness, irritation, coughing, headache if large amounts inhaled.
Potential Health Effects: Prolonged exposure may aggravate pre-existing respiratory or skin conditions.
Chemical Name: 1,2-Hexanediol
Concentration: ≥99% (by weight)
Impurities: None of known significant health hazard at this purity.
Molecular Weight: 118.17 g/mol
EC Number: 230-029-6
Inhalation: Move to fresh air right away. Seek medical attention if breathing becomes difficult.
Skin Contact: Remove contaminated clothing. Wash skin thoroughly with soap and water for at least 15 minutes. Seek advice if irritation persists.
Eye Contact: Rinse cautiously with water for several minutes. Lift eyelids to ensure complete rinsing. Remove contact lenses if present and easy to do. Get medical attention if irritation continues.
Ingestion: Rinse mouth; do not induce vomiting. Drink water to dilute and get medical help if feeling unwell or symptoms develop.
Note for Physician: Symptomatic and supportive treatment. No specific antidote known.
Flammability: Not highly flammable. May burn at high temperature.
Suitable Extinguishing Media: Water spray, dry chemical powder, foam, carbon dioxide.
Unsuitable Extinguishing Media: Direct water jets that spread burning material.
Hazards from Combustion: May produce carbon monoxide and carbon dioxide in fire.
Protective Equipment for Firefighters: Use self-contained breathing apparatus and full protective gear.
Fire Fighting Instructions: Keep cool all nearby containers. Move containers from fire area if possible and safe. Contain any runoff to avoid environmental contamination.
Personal Precautions: Make sure to avoid breathing vapors and contact with skin or eyes. Use proper protective gear such as gloves, goggles, and, if large spill, face shield.
Environmental Precautions: Prevent entry into waterways, drains, or sewers. Notify authorities if large spills cannot be contained.
Methods for Cleanup: Absorb spill with inert material (sand, earth, vermiculite). Collect in suitable container for proper disposal.
Other Information: Wash spill area thoroughly with water and detergent. Ventilate area after cleanup.
Safe Handling: Use with adequate ventilation. Avoid inhaling vapor. Avoid contact with skin, eyes, and clothing. Practice good industrial hygiene – wash hands before eating, drinking, or smoking.
Storage Requirements: Store in tightly closed original container. Keep in cool, dry, well-ventilated location away from acids, oxidizers, and direct sunlight. Store below 30°C/86°F preferred.
Incompatible Materials: Strong oxidizers, strong acids, and strong bases can react and should not be stored near this product.
Packing Materials: Use container compatible with diol and keep it labeled and sealed.
Occupational Exposure Limit: No OEL established under OSHA, ACGIH, NIOSH, or EU limits.
Engineering Controls: Ensure good general room ventilation. Use exhaust ventilation for high vapor generating tasks.
Personal Protective Equipment: Wear chemical splash goggles, suitable gloves (nitrile, latex, neoprene), protective clothing, closed shoes. Use approved respirators if airborne concentrations approach irritating levels.
General Hygiene: Wash exposed skin after handling. Do not eat, drink or smoke while working with product.
Appearance: Clear, colorless liquid
Odor: Mild, sweet odor
Odor Threshold: Not determined
pH: 6.0 – 8.0 (aqueous solution)
Melting Point: -40°C / -40°F
Boiling Point: 224°C / 435°F
Flash Point: >100°C / 212°F (closed cup)
Evaporation Rate: Not established
Flammability (solid, gas): Not applicable – liquid
Vapor Pressure: <0.01 mmHg (25°C)
Vapor Density: Heavier than air
Relative Density: 0.95 – 0.97 (water = 1)
Solubility: Miscible in water
Partition coefficient (log Kow): Estimated -0.02
Auto-Ignition Temperature: >250°C / >482°F
Decomposition Temperature: Not established
Viscosity: 55 mPa.s (20°C)
Chemical Stability: Stable under normal ambient and anticipated storage and handling conditions.
Reactivity: Low; reacts with strong oxidizing agents and acids.
Conditions to Avoid: Excessive heat, open flame, sources of ignition, contact with incompatible materials.
Hazardous Decomposition Products: Thermal decomposition can generate carbon monoxide and carbon dioxide.
Polymerization: Not expected to occur.
Incompatibilities: Strong oxidizers and acids.
Routes of Exposure: Inhalation, ingestion, skin and eye contact.
Acute Oral Toxicity: LD50 (rat) > 5000 mg/kg (low toxicity)
Acute Dermal Toxicity: LD50 (rabbit) > 2000 mg/kg (low toxicity)
Acute Inhalation Toxicity: No data available; not expected to be hazardous with normal use.
Skin Corrosion/Irritation: Causes mild, reversible irritation on prolonged contact.
Eye Damage/Irritation: Slightly irritating to eyes.
Respiratory or Skin Sensitization: No evidence of sensitization.
Mutagenicity: No evidence of mutagenic effects.
Carcinogenicity: No evidence in animal studies or classification by IARC, NTP, ACGIH, or OSHA.
Reproductive Toxicity: Not classified as reproductive toxicant.
Ecotoxicity: Low aquatic toxicity expected based on structure and similar chemicals.
Aquatic Toxicity (Fish): LC50 (96 h, fish): >100 mg/L
Aquatic Toxicity (Daphnia): EC50 (48 h): >100 mg/L
Algae Toxicity: EC50 (72 h): >100 mg/L
Persistence and Degradability: Biodegradable; rapid breakdown observed under aerobic conditions in environment.
Bioaccumulative Potential: Low; log Kow suggests low potential to bioaccumulate.
Mobility in Soil: Very mobile; miscible in water and can leach into soil.
Other Adverse Effects: No major environmental impact anticipated at normal release levels.
Waste Disposal Methods: Use appropriate local, regional, or national regulations for waste disposal. Do not pour into drains or waterways.
Reuse/Recycling: Consider recycling or reclaiming where permitted.
Container Disposal: Triple rinse empty container, offer for recycling or reconditioning where available. Dispose as hazardous waste if contaminated.
Special Precautions: Consult waste handler or environmental agency for guidance if in doubt.
UN Number: Not regulated as dangerous goods
UN Proper Shipping Name: Not classified as hazardous for transport
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Environmental Hazards: Not a marine pollutant
Special Precautions for User: No special requirements under normal conditions
Global Inventories: Listed in TSCA (US), EINECS/ELINCS (EU), ENCS (Japan), DSL (Canada), AICS (Australia), and others.
Regulatory Status: Not subject to major chemical restrictions worldwide; not regulated as dangerous for supply or transport.
Labeling Requirements: Avoid contact with eyes and skin; practice good hygiene. Follow product safety labeling for end use.
Other Regulations: OSHA: Not regulated as hazardous; SARA Title III: Not listed; California Proposition 65: Not listed; REACH (EU): Registered for relevant uses.
